摘要 |
The present disclosure relates to, inter alia, antibodies, or antigen-binding fragments thereof, that bind to C5a and to use of the antibodies in methods for treating or preventing complement-associated disorders such as, but not limited to, atypical hemolytic uremic syndrome, age-related macular degeneration, rheumatoid arthritis, sepsis, severe burn, antiphospholipid syndrome, asthma, lupus nephritis, Goodpasture's syndrome, and chronic obstructive pulmonary disease. |
申请人 |
ALEXION PHARMACEUTICALS, INC. |
发明人 |
ZHANG, YUCHUN;ROTHER, RUSSELL P.;TAMBURINI, PAUL P.;SHERIDAN, DOUGLAS L. |