| 发明名称 |
GLYCOSYLATED ANTITUMOR ETHER LIPIDS AS NOVEL CANCER STEM CELL CYTOTOXIC AGENTS |
| 摘要 |
Glycosylated antitumor ether lipids (GAELs) are effective cytotoxic agents against cancer stem cells. Furthermore, combining GAELs which kill cells by a caspase-independent pathway with agents that kill cells by apoptosis will lead to elimination of the differentiated tumor cells and the undifferentiated cancer stem cells leading to an elimination of the tumor and preventing recurrence. |
| 申请公布号 |
US2015011486(A1) |
申请公布日期 |
2015.01.08 |
| 申请号 |
US201314377551 |
申请日期 |
2013.02.08 |
| 申请人 |
UNIVERSITY OF MANITOBA |
发明人 |
Arthur Gilbert;Schweizer Frank;Samadder Pranati;Xu Yaozu |
| 分类号 |
C07H15/14;C07H7/02;C07H15/04 |
主分类号 |
C07H15/14 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of killing cancer stem cells and cancer stem cell spheroids by administering an effective amount of a compound selected from the group consisting of: |
| 地址 |
Winnipeg CA |
