Methods of Reducing the Risk of Mortality Associated With a Medical Treatment

摘要

Disclosed are methods of treatment that permit a reduction of risk of mortality in infants who are candidates for treatment with inhaled nitric oxide, by identifying a subset of such infants who are at an increased risk of mortality upon treatment with inhaled nitric oxide; also disclosed are related systems for use in administering inhaled nitric oxide and methods of distributing a pharmaceutical product.

主权项

1. A method of treatment comprising
(a) identifying a plurality of neonates as being candidates for treatment with inhaled nitric oxide; (b) determining that the race of a first neonate of the plurality is black; (c) administering inhaled nitric oxide to the first neonate; (d) determining that the race of a second neonate of the plurality is white; (e) determining that the gender of the second neonate is male; (f) determining that the second neonate is of less than 27 weeks gestational age; (g) determining that the fact that the second neonate is a white male of less than 27 weeks gestational age means the second neonate is at a higher risk of mortality upon administration of inhaled nitric oxide compared to a black male or female neonate of the same gestational age; and (h) excluding the second neonate from treatment with inhaled nitric oxide, based on the determination of (g).