发明名称 |
COMPOSITIONS AND METHODS FOR USE IN MEDICAL DIAGNOSIS |
摘要 |
The present invention relates to compositions and methods for use in medical diagnosis and patient's monitoring. It more particularly relates to a biocompatible gel comprising nanoparticles and/or nanoparticles aggregates, wherein i) the nanoparticle and/or nanoparticles aggregate comprise an inorganic material comprising at least one metal element having an atomic number Z of at least 25, each of said nanoparticle and of said nanoparticles aggregate being covered with a biocompatible coating; ii) the nanoparticles and/or nanoparticles aggregates concentration is of about or less than 0.5% (w/w); and iii) the apparent viscosity at 2s - of the gel comprising nanoparticles and/or nanoparticles aggregates, is between about 0.1 Pa.s and about 1000 Pa.s when measured between 20°C and 37°C. 1 The composition of the invention typically allows the delineation and visualization of at least 40% of the target biological tissue when said tissue is observed using an X-ray imaging equipment. |
申请公布号 |
WO2014202723(A1) |
申请公布日期 |
2014.12.24 |
申请号 |
WO2014EP62947 |
申请日期 |
2014.06.19 |
申请人 |
NANOBIOTIX |
发明人 |
POUL, LAURENCE;LEVY, LAURENT;BERJAUD, CÉLINE;GERMAIN, MATTHIEU;POTTIER, AGNÈS |
分类号 |
A61K9/51;A61K9/08;A61K47/48 |
主分类号 |
A61K9/51 |
代理机构 |
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