PHARMACEUTICAL COMPOSITION CONTAINING TP12 EXPRESSION INHIBITOR OR ACTIVITY INHIBITOR AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING RENAL CELL CANCER

摘要

The present invention relates to a pharmaceutical composition containing a Tp12 expression inhibitor or an activity inhibitor as an active ingredient for preventing or treating renal cancer. When the expression or activity of Tp12 according to the present invention is inhibited in renal cell cancer cells, the proliferation, anoikis resistance, cell adhesion capacity, cell migration capacity, and cell invasion capacity of cancer cells are degraded. When the Tp12 expression-inhibited renal cell cancer cells are transplanted into a mouse, the tumor growth and tumor metastasis to the lungs are inhibited. Therefore, the Tp12 expression inhibitor or activity inhibitor can be useful in preventing or treating renal cell cancer.