PEPMIXES TO GENERATE MULTIVIRAL CTLS WITH BROAD SPECIFICITY
摘要
<p>The present invention concerns methods of generating CTLs that are able to target at least one antigen from two or more viruses. The method includes exposing mixtures of peptides for different antigens to the same plurality of PBMCs and, at least in certain aspects, expanding the cells in the presence of IL4 and IL7.</p>
申请公布号
EP2812431(A1)
申请公布日期
2014.12.17
申请号
EP20130746524
申请日期
2013.02.08
申请人
BAYLOR COLLEGE OF MEDICINE
发明人
LEEN, ANNE, MARIE;VALDES, JUAN, FERNANDO VERA;ROONEY, CLIONA, M.;GERDEMANN, ULRIKE