发明名称 ANTI-VEGF ANTIBODY, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING, DIAGNOSING OR TREATING CANCER OR ANGIOGENESIS-RELATED DISEASES, CONTAINING SAME
摘要 The present invention relates to: a novel anti-vascular endothelial growth factor (VEGF) antibody having a strong binding affinity to VEGF and capable of inhibiting in vivo tumor growth; and a composition for treating cancer, containing the same. The antibody of the present invention shows a remarkable binding property to human and mouse VEGF, inhibits the proliferation and permeability of a human umbilical vein endothelial cell (HUVEC) and can suppress tumor growth, and thus can be useful as an antibody for treating cancer.
申请公布号 WO2014193191(A1) 申请公布日期 2014.12.04
申请号 WO2014KR04858 申请日期 2014.05.30
申请人 DONG-A SOCIO HOLDINGS CO., LTD.;IBIO, INC. 发明人 DOH, HYOUNMIE;KIM, BYONG MOON;KIM, CHAE YOUNG;LEE, SUNG-HEE;KIM, DONG-HYEON;KIM, YOO-JIN;LEE, DONGSOP;HAN, KYUNG MI;SONG, DONGSUP;JUNG, EUN-EE;LEE, JINSEOK;SEUNG, WOO JIN;SOHN, YOUNGSUN;HWANG, KYUSANG;HAN, BYUNGYOUL
分类号 C07K16/22;A61K39/395;A61P35/00;C12N15/13 主分类号 C07K16/22
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