| 发明名称 | Mitochondria-targeted antioxidants | ||
| 摘要 | The present invention relates to a pharmaceutical or veterinary or nutritional or personal care composition comprising coenzyme Q10 (CoQ10), reduced CoQ10, or mixtures thereof and oxygenated dibenzo-α-pyrone or an amino acyl ester thereof. The composition of the present invention is able to support and/or provide therapy to individuals at risk and/or under treatment for dysfunctions of energy metabolism, and specifically, for mitochondrial diseases. | ||
| 申请公布号 | US8894993(B2) | 申请公布日期 | 2014.11.25 |
| 申请号 | US200711881630 | 申请日期 | 2007.07.27 |
| 申请人 | Natreon Inc.;Indian Herbs Research & Supply Company, Ltd. | 发明人 | Ghosal Shibnath |
| 分类号 | A61K38/43;A61K38/54;A61K31/122;A23L1/30;A23L2/52;A61K8/34;A61K8/44;A61K31/37;A61K35/10;A61Q19/08;A61Q17/04 | 主分类号 | A61K38/43 |
| 代理机构 | Porzio, Bromberg & Newman, P.C. | 代理人 | Porzio, Bromberg & Newman, P.C. |
| 主权项 | 1. A method of treating a mitochondrial disorder comprising administering to a subject suffering from a mitochondrial disorder a composition comprising purified (a) Coenzyme Q10 (CoQ10), reduced CoQ10, or mixtures thereof, and (b) oxygenated dibenzo-α-pyrone or an amino acyl ester thereof wherein the composition is orally administered to an adult at least 5 mg per day of the composition and 3-OS-DBP is systemically converted to 3,8(OH)2-DBP. | ||
| 地址 | New Brunswick NJ US | ||