HIDTIL UKENDTE FORBINDELSER, ISOMER DERAF, ELLER FARMACEUTISK ACCEPTABLE SALTE DERAF SOM VANILLOID RECEPTORANTAGONIST OG FARMACEUTISKE SAMMENSÆTNINGER INDEHOLDENDE SAMME

摘要

This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1)antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, heart disease and so on.