发明名称 |
TREATMENT OF TINNITUS THROUGH MODULATION OF CHLORIDE CO-TRANSPORTER NKCC1 IN THE AUDITORY SYSTEM |
摘要 |
The present invention relates to the treatment or prevention of tinnitus. More precisely, the present invention relates to a compound modulating chloride co-transporter NKCC1 (chloride co-transporter modulator) for use in the treatment of tinnitus. In addition, the present invention concerns pharmaceutical compositions comprising such an NKCC1 chloride co-transporter modulator as an active agent, a method for the treatment or prevention of tinnitus by administering such a chloride co-transporter modulator, and a screening method for the identification and characterization of compounds capable of modulating chloride co-transporter NKCC1. |
申请公布号 |
EP2790686(A1) |
申请公布日期 |
2014.10.22 |
申请号 |
EP20110804529 |
申请日期 |
2011.12.12 |
申请人 |
AURIS MEDICAL AG |
发明人 |
KNIPPER, MARLIES;RUETTIGER, LUKAS |
分类号 |
A61K31/00;A61K31/195;A61K31/40;A61K31/404;A61K31/425;A61K31/549;A61K31/635;A61K31/64;A61P27/16 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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