发明名称 MÉTODO PARA PRODUZIR UMA CÉLULA CAPAZ DE PRODUÇÃO DE ALTO RENDIMENTO DE HETEROPROTEÍNAS.
摘要 The present invention provides a cell capable of high-yield production of polypeptides and a method for producing the same. The present invention relates to a method for producing a cell capable of high-yield production of a desired polypeptide, wherein a strongly taurine transporter-expressing cell into which DNA encoding the desired polypeptide has been introduced is cultured in the presence of a high concentration of methotrexate and a cell capable of high-yield production of the desired polypeptide is selected from among surviving cells.
申请公布号 BRPI0818039(A2) 申请公布日期 2014.10.14
申请号 BR2008PI18039 申请日期 2008.10.14
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 HISAHIRO TABUCHI;TOMOYA SUGIYAMA
分类号 C12N15/09;C12N5/10;C12P21/02 主分类号 C12N15/09
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