发明名称 |
MÉTODO PARA PRODUZIR UMA CÉLULA CAPAZ DE PRODUÇÃO DE ALTO RENDIMENTO DE HETEROPROTEÍNAS. |
摘要 |
The present invention provides a cell capable of high-yield production of polypeptides and a method for producing the same. The present invention relates to a method for producing a cell capable of high-yield production of a desired polypeptide, wherein a strongly taurine transporter-expressing cell into which DNA encoding the desired polypeptide has been introduced is cultured in the presence of a high concentration of methotrexate and a cell capable of high-yield production of the desired polypeptide is selected from among surviving cells. |
申请公布号 |
BRPI0818039(A2) |
申请公布日期 |
2014.10.14 |
申请号 |
BR2008PI18039 |
申请日期 |
2008.10.14 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
HISAHIRO TABUCHI;TOMOYA SUGIYAMA |
分类号 |
C12N15/09;C12N5/10;C12P21/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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