| 发明名称 |
RNAI AGENTS, COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING TRANSTHYRETIN (TTR) ASSOCIATED DISEASES |
| 摘要 |
The present invention provides RNAi agents, e.g., double stranded RNAi agents, that target the transthyretin (TTR) gene and methods of using such RNAi agents for treating or preventing TTR-associated diseases. |
| 申请公布号 |
EP2780353(A1) |
申请公布日期 |
2014.09.24 |
| 申请号 |
EP20120850255 |
申请日期 |
2012.11.16 |
| 申请人 |
ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
RAJEEV, KALLANTHOTTATHIL, G.;ZIMMERMANN, TRACY;MANOHARAN, MUTHIAH;MAIER, MARTIN;KUCHIMANCHI, SATYANARAYANA;CHARISSE, KLAUS |
| 分类号 |
C12N15/11;A61K31/7125;A61K31/713;C12N15/113 |
主分类号 |
C12N15/11 |
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