| 发明名称 |
Identification and characterization of a specific CCK-C receptor antibody for human pancreatic cancer and its use for early detection and staging of pancreatic cancer |
| 摘要 |
Human pancreatic cancer cells possess a distinct plasma membrane CCK receptor variant that can be differentiated from the classic CCK-B receptor with selective monoclonal antibodies. Use of this receptor may be helpful in early detection or treatment of patients with pancreatic cancer. |
| 申请公布号 |
US8821872(B2) |
申请公布日期 |
2014.09.02 |
| 申请号 |
US201012772758 |
申请日期 |
2010.05.03 |
| 申请人 |
|
发明人 |
Smith Jill P.;Matters Gail L.;Christensen Neil D.;Harms John F. |
| 分类号 |
A61K39/395;G01N33/53;C07K16/30;C12P21/08;B82Y5/00 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
Weinberger Laurence A. |
| 主权项 |
1. The 3B9.1 monoclonal antibody to the CCK-C receptor which receptor is a splice variant receptor of the CCK-B receptor that retains the 4th intron (also called CCK2Ri4sv). |
| 地址 |
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