发明名称 |
Pharmaceutical composition for treating hypertension and metabolic syndrome and use thereof |
摘要 |
The present invention provides a pharmaceutical composition comprising the following active ingredients: 1) an angiotensin II receptor antagonist or a pharmaceutically acceptable salt thereof, 2) pioglitazone or a pharmaceutically acceptable salt thereof; and 3) rosuvastatin or a pharmaceutically acceptable salt thereof. The present invention also provides use of the pharmaceutical composition in preparing a medicament for treating hypertension or metabolic syndrome. The pharmaceutical composition of the present invention can treat hypertension or metabolic syndrome, while effectively controlling the incidence of associated cardiovascular diseases and more potently improving survival prognosis in hypertensive patients. When blood pressure is lowered to desired level, the risk factors such as cardiovascular diseases are rectified, metabolic disorders and prognosis of patients are improved, and survival rate of hypertensive patients is raised. |
申请公布号 |
US8815286(B2) |
申请公布日期 |
2014.08.26 |
申请号 |
US200913055481 |
申请日期 |
2009.07.23 |
申请人 |
Lunan Pharmaceutical Group Corporation |
发明人 |
Zhao Zhiquan |
分类号 |
A61K9/20;A01N43/00;A61K31/50;A61K9/48;A61K31/4184;A61K45/06;A61K31/505;A61K31/519;A61K31/4439;A61K31/4178;A61K9/16;A61K31/41;A61K9/00;A61K9/24 |
主分类号 |
A61K9/20 |
代理机构 |
Renner, Otto, Boisselle & Sklar, LLP |
代理人 |
Renner, Otto, Boisselle & Sklar, LLP |
主权项 |
1. A pharmaceutical composition, wherein the pharmaceutical composition comprises therapeutically effective amounts of the following active ingredients:
1) losartan or a pharmaceutically acceptable salt thereof; 2) pioglitazone or a pharmaceutically acceptable salt thereof; and 3) rosuvastatin or a pharmaceutically acceptable salt thereof, wherein the composition is effective in the treatment of hypertension. |
地址 |
Linyi, Shandong Province CN |