Serpinf2-Binding Molecules and Method of Use Thereof

摘要

Compositions and methods of using SerpinF2-binding molecules for preventing and/or reducing organ damage, functional disability or mortality in a patient at risk due to the activity of SerpinF2 and/or plasminogen activators on tissue injury. Also provided are compositions and methods of using SerpinF2-binding molecules for inhibiting hemorrhage, edema, and apoptosis. Methods for the preparation of medicaments for such methods of treatment and prevention are provided.

主权项

1. A method of inhibiting disability or death from hemorrhage or edema in a patient in need thereof comprising administering to the patient an effective amount of a SerpinF2-binding molecule that reduces SerpinF2 activity or concentration, thereby inhibiting disability or death from hemorrhage or edema in the patient.