| 发明名称 |
(22E)-2-METHYLENE-22-DEHYDRO-1α,24,25-TRIHYDROXY-19-NOR-VITAMIN D3 ANALOGS |
| 摘要 |
Disclosed are (22E)-2-methylene-22-dehydro-1,24,25-trihydroxy-19-nor-vitamin D3 compounds, their biological activities, and various pharmaceutical uses for these compounds. Particularly disclosed are (22E )-(24R)-2-methylene-22-dehydro-1α,24,25-trihydroxy-19-nor-viiamin D3 and (22E)-(24S)-2-methylene-22-dehydro-1α,24,25-triliydroxy-19-nor-vitamin D3, their biological activities, and various pharmaceutical uses for these compounds. |
| 申请公布号 |
WO2014116386(A1) |
申请公布日期 |
2014.07.31 |
| 申请号 |
WO2013US77486 |
申请日期 |
2013.12.23 |
| 申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
DELUCA, HECTOR, F.;PLUM, LORI, A.;BARYACKI, RAFAL;CLAGETT-DAME, MARGARET |
| 分类号 |
C07C401/00;A61K31/592;A61K31/593;A61P3/02;A61P3/04;A61P5/18;A61P17/00;A61P17/06;A61P19/10;A61P35/00 |
主分类号 |
C07C401/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
