Glycosylceramide adjuvant for saccharide antigens

摘要

The invention provides compositions and kits comprising: (a) a saccharide antigen conjugated to a carrier; and (b) an alpha-glycosylceramide adjuvant. The invention further provides uses of the compositions. It has been found that suppression of anti-saccharide immune responses by alpha-glycosylceramides can be reversed by conjugating the saccharide to a carrier.

主权项

1. A composition comprising: (a) an immunologically effective amount of a saccharide antigen that is conjugated to a carrier; and (b) an α-glycosylceramide adjuvant.