| 摘要 |
Provided is a compound of formula (I):;;or a pharmaceutically acceptable salt thereof. Also provided is a method of treating, prophylaxis, or amelioration of a disease, comprising administering to a subject in need of treatment for the disease an effective amount of a compound of formula (I) described herein. In one embodiment, the method is a neurodegenerative disease, such as multiple sclerosis, amyotrophic lateral sclerosis, Parkinson's disease, Huntington's disease, or Alzheimer's disease. |
| 主权项 |
1. A compound of formula (I) (a) or a pharmaceutically acceptable salt thereof, wherein (b) each, of R1 and R2, independently, is hydrogen, deuterium, deuterated methyl, deuterated ethyl, C1-6 aliphatic, phenyl, 3-7 membered saturated or partially unsaturated monocyclic carbocyclic ring, 3-7 membered saturated or partially unsaturated monocyclic heterocyclic ring having 1-3heteroatoms independently selected from nitrogen, oxygen, and sulfur, or a 5-6 membered heteroaryl ring having 1-3 heteroatoms independently selected from nitrogen, oxygen, and sulfur, and (c) each of R3 and R4, independently, is hydrogen or deuterium, wherein at least one of R3 and R4 is deuterium and provided R1 and R2 are not hydrogen at the same time. |
