| 发明名称 |
METHODS OF MODULATING COMPLIANCE OF THE TRABECULAR MESHWORK |
| 摘要 |
The present invention relates to method, system, and composition for modulating the compliance of the trabecular meshwork, which may provide treatment to glaucoma. |
| 申请公布号 |
US2014187607(A1) |
申请公布日期 |
2014.07.03 |
| 申请号 |
US201314134991 |
申请日期 |
2013.12.19 |
| 申请人 |
The Regents of The University of California |
发明人 |
RUSSELL Paul;MURPHY Christopher J.;THOMASY Sara M.;RAGHUNATHAN Vijay Krishna;MORGAN Joshua T.;WOOD Joshua |
| 分类号 |
C12N15/113;C07D493/06 |
主分类号 |
C12N15/113 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of reducing intraocular pressure in a subject in need thereof, comprising administering to the subject an effective amount of an agent that inhibits the function of Yes-associated protein (YAP) transcriptional co-activator/transcriptional co-activator with PDZ binding motif (TAZ), thereby reducing intraocular pressure in the subject. |
| 地址 |
Oakland CA US |
