发明名称 |
METHOD FOR PRODUCING PLURIPOTENTIAL CELLS |
摘要 |
The invention relates to biotechnology, namely to the production of pluripotential cells. The method involves introducing RNA into the cells of an umbilical-placental complex, which RNA has at least one sequence that provides for the transition of the cells into a pluripotential state. The method makes it possible to efficiently produce pluripotential cells from the umbilical-placental complex cells that do not yet acquire somatic mutations, thereby reducing the probability of oncogenesis and other negative consequences of reprogramming. |
申请公布号 |
EA019719(B1) |
申请公布日期 |
2014.05.30 |
申请号 |
EA20110001288 |
申请日期 |
2010.03.03 |
申请人 |
OBSCHESTVO S OGRANICHENNOJ OTVETSTVENNOST'JU "LABORATORIJA KLETOCHNYKH TEKHNOLOGIJ" |
发明人 |
KISELJOV SERGEJ, L'VOVICH;LAGAR'KOVA MARIJA, ANDREEVNA;SHUTOVA MARIJA, VLADIMIROVNA |
分类号 |
C12N5/10 |
主分类号 |
C12N5/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|