| 摘要 |
<p>PROBLEM TO BE SOLVED: To provide a screening method for periodontal disease improving or preventing agents, the method useful for simple and accurate screening for the periodontal disease improving or preventing agents useful for prevention and improvement of periodontal disease.SOLUTION: In a screening method for periodontal disease improving or preventing agents, a bacterium having a quorum-sensing system via autoinducer-2 and a test agent are mixed, and the test agent having autoinducer-2 activity inhibitory effect is selected as periodontal disease improving or preventing agents.</p> |
