发明名称 |
A COMPUTER-IMPLEMENTED SYSTEM AND METHOD FOR THE PREDICTION OF CANCER RESPONSE TO GENOTOXIC CHEMOTHERAPY AND PERSONALISED NEOADJUVANT TREATMENTS (PCCP) |
摘要 |
<p>A method for predicting an individual's response to a treatment for cancer, the method comprising a step of assaying a biological sample from the individual to determine the abundance of a panel of two or more bio-markers comprising pro-apoptotic and/or anti-apoptotic biomarkers; inputting the abundance value for the two bio-markers into a computational model of a mitochondrial apoptosis pathway; and processing said abundance values using said computational model to provide a value to predict the individual's response to treatment.</p> |
申请公布号 |
EP2727037(A1) |
申请公布日期 |
2014.05.07 |
申请号 |
EP20120740317 |
申请日期 |
2012.06.28 |
申请人 |
ROYAL COLLEGE OF SURGEONS IN IRELAND |
发明人 |
PREHN, JOCHEN;HUBER, HEINRICH;REHM, MARKUS |
分类号 |
G06F19/12 |
主分类号 |
G06F19/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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