发明名称 |
I-CreI meganuclease variants with modified specificity, method of preparation and uses thereof |
摘要 |
Method of preparing I-CreI meganuclease variants having a modified cleavage specificity, variants obtainable by said method and their applications either for cleaving new DNA target or for genetic engineering and genome engineering for non-therapeutic purposes. Nucleic acids encoding said variants, expression cassettes comprising said nucleic acids, vectors comprising said expression cassettes, cells or organisms, plants or animals except humans, transformed by said vectors. |
申请公布号 |
US8715992(B2) |
申请公布日期 |
2014.05.06 |
申请号 |
US201213422902 |
申请日期 |
2012.03.16 |
申请人 |
DUCHATEAU PHILIPPE;PAQUES FREDERIC;CELLECTIS |
发明人 |
DUCHATEAU PHILIPPE;PAQUES FREDERIC |
分类号 |
C12N9/00;C07H21/04;C12N1/20;C12N9/22;C12N15/00 |
主分类号 |
C12N9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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