发明名称 LIPOPHILIC BIOACTIVE THERAPEUTIC SAPROPELIC MUD EXTRACT AND PROCESS FOR OBTAINING THE SAME
摘要 <p>The invention relates to a bioactive extract with anti-oxidizing action and regeneration, stimulation and UV radiation shielding effect, and to a process for obtaining the same. According to the invention, the extract comprises 15...17% compounds with saturated hydrocarbon chains, 55...56% organic compounds with oxygen, 24...25% compounds with nitrogen and sulphur, 1.5...2% aromatic hydrocarbons and 0.2...0.5% beta-carotene. The process claimed by the invention consists in extracting the dried and powdered sapropelic mud, previously wetted with distilled water, with a mixture of 2:1 methanol:chloroform, separating the suspension by centrifuging, bringing the residue after the first extraction to a pH 3.5...4 with hydrochloric acid 0.2 N, followed by pellet extraction, while uniting the two supernatants resulting after extraction, separating the chloroform phase by adding distilled water, neutralizing the same with alcohol solution of potassium hydroxide 1 N, extracting the residual pellet with benzene, while finally uniting the chloroform phase and the benzene phase and evaporating the solvents to result a lipophilic waxy mud extract which is conditioned.</p>
申请公布号 RO127870(B1) 申请公布日期 2014.04.30
申请号 RO20120000040 申请日期 2012.01.19
申请人 UNIVERSITATEA "OVIDIUS" DIN CONSTAN&Tcedil,A 发明人 BRATU MIHAELA-MIRELA;NEGREANU-PÎRJOL TICU&Tcedil,A;SURDU OLGA;DOROFTEI ELENA;HO&Scedil,TIN&Abreve, CORINA;MIRE&Scedil,AN HORA&Tcedil,IU;RONCEA FLORENTINA NICOLETA
分类号 A61K35/04;A61P17/00 主分类号 A61K35/04
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