| 发明名称 |
INDOL-AMIDE COMPOUNDS AS BETA-AMYLOID INHBITORS |
| 摘要 |
The present invention provides compounds of formula (I), wherein Z, R1, R2, and R3 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments for the treatment of Alzheimer's disease. |
| 申请公布号 |
WO2014060386(A1) |
申请公布日期 |
2014.04.24 |
| 申请号 |
WO2013EP71478 |
申请日期 |
2013.10.15 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG;HOFFMANN-LA ROCHE INC. |
发明人 |
BAUMANN, KARLHEINZ;FLOHR, ALEXANDER;JOLIDON, SYNESE;KNUST, HENNER;LUEBBERS, THOMAS;NETTEKOVEN, MATTHIAS |
| 分类号 |
C07D401/14;A61K31/404;A61K31/454;A61K31/497;A61P25/00;C07D401/04;C07D401/06;C07D403/04;C07D403/06;C07D405/04;C07D405/14 |
主分类号 |
C07D401/14 |
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