发明名称 CEPHALOSPORINS HAVING CATECHOL GROUP
摘要 PROBLEM TO BE SOLVED: To provide a cephem compound having wide antibacterial spectrum against various bacteria including gram-negative bacterium and/or gram-positive bacterium, and to provide a pharmaceutical composition containing the same.SOLUTION: There are provided: a compound represented by formula (I), where X is N, CH or C-Cl, T is S or the like, A and G are each a lower alkylene or the like, B is a single bond or the like, D is a single bond, -NR-CO-, -CO-NR-, -NR-CO-NR-, or the like, E is a lower alkylene which may be substituted, H is a single bond, or phenylene which may be substituted, R, R, Rand Rare each independently a hydrogen, a halogen, nitrile, or the like; an ester of the compound represented by the formula (I); a protected compound obtained by protecting an amino group on a ring in a 7-position side chain of the compound represented by the formula (I); and pharmaceutically acceptable salts and solvates of them.
申请公布号 JP2014065732(A) 申请公布日期 2014.04.17
申请号 JP20130259499 申请日期 2013.12.16
申请人 SHIONOGI & CO LTD 发明人 NISHITANI YASUHIRO;YAMAWAKI KENJI;TAKEOKA YUSUKE;SUGIMOTO HIDEKI;HISAKAWA SHINYA;AOKI TOSHIAKI
分类号 C07D501/24;A61K31/5365;A61K31/546;A61K31/55;A61P31/04;C07D505/00;C07D519/06 主分类号 C07D501/24
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