| 发明名称 |
PIPERAZINYL 3-AMINOPYRROLIDINE DERIVATIVES AS A CCR2 ANTAGONIST |
| 摘要 |
<p>The present invention relates to compounds of chemical formula I and having CCR2 (chemokine receptor 2) antagonistic effects, and salts or isomers thereof. These compounds are very useful for treating, preventing, or relieving rheumatoid arthritis, arteriosclerosis, multiple sclerosis, asthma, and various diseases related to CCR2.
wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 and R 9 is the same as defined in the specification.</p> |
| 申请公布号 |
EP2452939(B1) |
申请公布日期 |
2014.03.26 |
| 申请号 |
EP20100797246 |
申请日期 |
2010.06.11 |
| 申请人 |
YANG JI CHEMICAL CO., LTD. |
发明人 |
LIM, JEE WOONG;KIM, JONG-HOON;OAK, MIN-HO;NA, YONGHO;OH, YOUNA;KANG, SO-HEE;LEE, JUNG-OK;SOHN, JUNG-DUK;LEE, SEUNG-WOO |
| 分类号 |
C07D207/14;A61K31/496;A61P9/10;A61P9/14;A61P17/00;A61P19/02;A61P29/00;A61P37/06;A61P37/08 |
主分类号 |
C07D207/14 |
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