| 发明名称 |
Interferon alpha-2B modified by polyethylene glycol and methods of preparation thereof |
| 摘要 |
The present invention relates to interferon-alpha2b modified with Y-shaped branched polyethylene glycol (PEG) at a single Lys residue and the preparation thereof. The peglated IFN-alpha2b can be used for the preparation of a medicament for treating a disease, e.g. viral infections such as Hepatitis C. |
| 申请公布号 |
US8597635(B2) |
申请公布日期 |
2013.12.03 |
| 申请号 |
US20100676525 |
申请日期 |
2010.06.07 |
| 申请人 |
ZHOU WEIDONG;XIAO QINGJIANG;SUN LI;WANG TIEBING;YIN FENGHONG;LUO SHIHONG;ZHUANG LU;LIU MIN;XU TIANLE;ZHANG YONG;BIOSTEED GENE EXPRESSION TECH. CO., LTD. |
发明人 |
ZHOU WEIDONG;XIAO QINGJIANG;SUN LI;WANG TIEBING;YIN FENGHONG;LUO SHIHONG;ZHUANG LU;LIU MIN;XU TIANLE;ZHANG YONG |
| 分类号 |
A61K38/21;A61K38/00;A61K39/385;C07K14/56 |
主分类号 |
A61K38/21 |
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