| 发明名称 |
METHOD OF PREPARING (+)-1,4-DIHYDRO-7-[(3S,4S)-3METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OXO-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID |
| 摘要 |
593763 Provided are methods of preparing (+)-1,4-dihydro-7-[(3S,4S)-3methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid, also known as voreloxin. Voreloxin is an anti-cancer agent. The methods aim to prepare a form of the compound that has less contamination by by-products. Also provided are methods for preparing specific intermediates of the methods. |
| 申请公布号 |
NZ593763(A) |
申请公布日期 |
2013.11.29 |
| 申请号 |
NZ20090593763 |
申请日期 |
2009.12.29 |
| 申请人 |
SUNESIS PHARMACEUTICALS, INC. |
发明人 |
RAHUMAN, MOHAMED SHEIK MOHAMED MUJEEBUR;SUBRAMANI, TAMILARASAN;SUBBIAH, RAMAR;SUDHAKAR, ANANTHA |
| 分类号 |
C07D471/04;A61K31/4375;A61P35/00;C07D207/14 |
主分类号 |
C07D471/04 |
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