发明名称 3,4-dihydro-1h-naphthalenones which are selective glucocorticoid receptor modulators
摘要 <p>The present invention provides non-steroidal compounds of formula I which are selective modulators (i.e., agonists and antagonists) of a steroid receptor, specifically, the glucocorticoid receptor. The present invention also provides pharmaceutical compositions containing these compounds and methods for using these compounds to treat animals requiring glucocorticoid receptor agonist or antagonist therapy. Glucocorticoid receptor modulators are useful to treat diseases, such as obesity, diabetes, inflammation and others as described below. The present invention also provides intermediates and processes for preparing these compounds.</p>
申请公布号 IL180603(A) 申请公布日期 2013.11.28
申请号 IL20070180603 申请日期 2007.01.08
申请人 PFIZER PRODUCTS INC. 发明人
分类号 C07C;C07D295/12;A61K31/05;A61K31/122;A61K31/27;A61K31/275;A61K31/325;A61K31/40;A61K31/4164;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4965;A61K31/5375;A61P3/04;A61P3/10;A61P11/06;A61P19/02;A61P25/22;A61P25/24;A61P25/28;A61P27/16;A61P29/00;A61P37/02;A61P43/00;C07C35/42;C07C49/675;C07C49/737;C07C49/747;C07C49/755;C07C49/757;C07C65/17;C07C69/00;C07C215/50;C07C215/74;C07C225/22;C07C233/58;C07C235/48;C07C235/66;C07C247/24;C07C251/44;C07C251/52;C07C251/60;C07C255/53;C07C255/54;C07C271/10;C07C271/44;C07C271/52;C07C281/04;C07C307/02;C07C309/65;C07C309/66;C07C309/73;C07C311/04;C07C311/08;C07C311/51;C07C317/18;C07C333/04;C07D207/09;C07D211/46;C07D213/22;C07D213/30;C07D213/40;C07D213/75;C07D231/40;C07D231/56;C07D233/61;C07D239/34;C07D241/12;C07D241/18;C07D241/20;C07D249/08;C07D249/14;C07D257/04;C07D271/06;C07D271/07;C07D277/24;C07D277/28;C07D277/56;C07D295/092;C07D295/13;C07D295/185;C07D295/205;C07D303/14;C07D317/36;C07D333/16;C07D413/04;C07D455/06 主分类号 C07C
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