发明名称 |
Design, synthesis and functional characterization of rottlerin analogs |
摘要 |
A method of synthesizing rottlerin analogs is described. The synthesis methods described are the first known method of synthesizing rottlerin analogs from commercially-available materials to produce cost effective analogs. Rottlerin analog structures made by the synthesis methods and methods of use for treating a neurological or inflammatory response mediated by protein kinase C (PKC) are further described.
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申请公布号 |
US8586768(B2) |
申请公布日期 |
2013.11.19 |
申请号 |
US20100945180 |
申请日期 |
2010.11.12 |
申请人 |
KANTHASAMY ANUMANTHA G.;KRAUS GEORGE A.;ANANTHARAM VELLAREDDY;IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. |
发明人 |
KANTHASAMY ANUMANTHA G.;KRAUS GEORGE A.;ANANTHARAM VELLAREDDY |
分类号 |
C07D311/58;A61K31/352;C07D311/70 |
主分类号 |
C07D311/58 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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