发明名称 |
DIAGNOSTIC DRUG AND DIAGNOSTIC METHOD FOR ALZHEIMER'S DISEASE |
摘要 |
<p>The present invention provides an agent for determining Alzheimer's disease, comprising an anti-S38AA antibody, a method of determining Alzheimer's disease in a test animal, comprising detecting an S38AA fragment in a sample collected from said animal, and a method of screening for a substance that treats or prevents Alzheimer's disease, comprising contacting a test substance with a cell permitting measurement of production of a S38AA fragment, measuring the production amount of the S38AA fragment in the cell, and comparing the production amount with that of the S38AA fragment in a control cell free of contact with the test substance, and selecting a test substance that down-regulates the production amount of the S38AA fragment as a substance capable of treating or preventing Alzheimer's disease, based on the comparison results.</p> |
申请公布号 |
EP2660600(A1) |
申请公布日期 |
2013.11.06 |
申请号 |
EP20110853134 |
申请日期 |
2011.12.28 |
申请人 |
DAINIPPON SUMITOMO PHARMA CO., LTD. |
发明人 |
HASHIMOTO, MASAKAZU;NAKAGAWA, HIROYUKI;AOKI, MIKIO;TJERNBERG, LARS O.;WINBLAD, BENGT |
分类号 |
G01N33/53;C07K16/18;C12N15/09;G01N33/15;G01N33/50 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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