发明名称 |
Methods and assays for identifying compounds that modulate protein-protein interactions |
摘要 |
Methods and assays for identifying a compound that modulates a protein-protein interaction between a first and a second protein. The methods and assays require a protease that is attached to the second protein and a split and rearranged reporter activating protein that is attached to the first protein, wherein the reporter activating protein comprises a cleavage site for the protease that is interposed between two portions of the reporter activating protein and wherein the two portions of the reporter activating protein are in a rearranged order. |
申请公布号 |
US8574865(B2) |
申请公布日期 |
2013.11.05 |
申请号 |
US20080676284 |
申请日期 |
2008.08.28 |
申请人 |
WRIGHT PAUL STEVEN;WEISSENSEE PAUL;EISHINGDRELO HAIFENG;CAI JIDONG;SANOFI |
发明人 |
WRIGHT PAUL STEVEN;WEISSENSEE PAUL;EISHINGDRELO HAIFENG;CAI JIDONG |
分类号 |
C12Q1/37 |
主分类号 |
C12Q1/37 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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