发明名称 |
PIMECROLIMUS FOAM COMPOSITION CONTAINING HEXYLENE GLYCOL, OPTIONALLY OLEYL ALCOHOL, DIMETHYLISOSORBIDE AND/OR MEDIUM CHAIN TRIGLYCERIDES |
摘要 |
<p>Pharmaceutical foam compositions substantially free of ethanol and comprising pimecrolimus in a carrier vehicle comprising a mixture of oily solvents amounting to at least 40% of the total weight of the composition and consisting of: i) hexylene glycol; ii) optionally oleyl alcohol; and iii) dimethylisosorbide and/or medium chain triglycerides; and additionally: iv) when oleyl alcohol is absent, water in an amount of less than 25%; v) at least one consistency agent; vi) at least one preservative; and vii) at least one surfactant/emulgator; and propellant gas for foaming; and optionally further conventional excipients. They are indicated for use in the treatment of various skin, nail and mucosal diseases.</p> |
申请公布号 |
EP1734927(B8) |
申请公布日期 |
2013.10.23 |
申请号 |
EP20050733580 |
申请日期 |
2005.04.07 |
申请人 |
MEDA PHARMA S.A.R.L. |
发明人 |
EINI, MEIR;FRIEDMAN, DORON;HIRSCH, STEFAN;MEYENBURG, SABINE;SEKKAT, NABILA;TAMARKIN, DOV |
分类号 |
A61K9/12;A61K9/00;A61K31/445;A61K47/10;A61K47/14;A61K47/26 |
主分类号 |
A61K9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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