| 发明名称 |
METHODS, ASSAYS AND COMPOUNDS FOR TREATING BACTERIAL INFECTIONS BY INHIBITING METHYLTHIOINOSINE PHOSPHORYLASE |
| 摘要 |
The present invention discloses methods for treating bacterial infections in a subject comprising administering to the subject a sub-growth inhibiting amount of a 5'-methylthioinosine phosphorylase (MTIP) inhibitor, as well as assays for identifying such inhibitors, and compounds and pharmaceutical compositions comprising the inhibitors.
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| 申请公布号 |
US2013274220(A1) |
申请公布日期 |
2013.10.17 |
| 申请号 |
US201113884298 |
申请日期 |
2011.11.28 |
| 申请人 |
SCHRAMM VERN L.;CLINCH KEITH;TYLER PETER CHARLES;EVANS GARY BRIAN;FURNEAUX RICHARD HUBERT;INDUSTRIAL RESEARCH LIMITED;ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY |
发明人 |
SCHRAMM VERN L.;CLINCH KEITH;TYLER PETER CHARLES;EVANS GARY BRIAN;FURNEAUX RICHARD HUBERT |
| 分类号 |
C07D487/04;A61K31/519;A61K45/06;C12Q1/48 |
主分类号 |
C07D487/04 |
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