发明名称 |
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OF UCH-L1 RELATED DISEASES CONTAINING UCH-L1 INHIBITOR OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS AN ACTIVE INGREDIENT |
摘要 |
PURPOSE: A UCH-L1 inhibitor has excellent UCH-L1 activation-inhibiting performance, especially for cancer cells, and has low cell cytotoxicity. CONSTITUTION: A pharmaceutical composition for preventing or treating UCH-L1-related diseases contains a compound represented by chemical formula 1. In chemical formula 1, each of R^1 and R^2 is hydrogen, a hydroxy group, a C1-4 linear or branched alkyl group; a C1-4 linear or branched alkoxy group; a carboxy group; an aldehyde group; an azide group; a nitro group; a sodium sulfonate group; a sulfonic acid group; or a substituted or unsubstituted amino group; R^3 is hydrogen or a hydroxy group; R^4 is hydrogen, iodine, a C1-4 linear or branched alkylidenyl group, or an azide group; each of R^5 and R^6 is hydrogen, C1-4 linear or branched alkyl group, or C2-4 linear or branched alkenyl; and R^7 is a C1-4 linear or branched alkyl group or C2-4 linear or branched alkylidenyl group. |
申请公布号 |
KR20130112519(A) |
申请公布日期 |
2013.10.14 |
申请号 |
KR20120034957 |
申请日期 |
2012.04.04 |
申请人 |
EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION |
发明人 |
LEE, KONG JOO;KIM, YOU HWA;KIM, HYUN JUNG;LEE, HEE YOON;JOUNG, SEE WON;JEONG, JAE EUN;SEO, EUN KYOUNG |
分类号 |
C07C43/23;A61K31/045;A61P35/00 |
主分类号 |
C07C43/23 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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