发明名称 Stabilization of liquid solutions of recombinant protein for frozen storage
摘要 The invention relates to a method for stabilizing a bulk solution of recombinant protein for frozen storage, which comprises providing a partially-purified solution of recombinant protein which has a monovalent salt concentration of at least 100 mM, and adding a carbohydrate to said solution in an amount sufficient that, upon freezing, the solution has a glass transition temperature of -56° C. or higher.
申请公布号 US8536125(B2) 申请公布日期 2013.09.17
申请号 US201213459806 申请日期 2012.04.30
申请人 TSVETKOVA NELLY;JOSHI OMKAR;WU PAUL;WANG DEQIAN;DESPONDS ARNAUD;BAYER HEALTHCARE LLC 发明人 TSVETKOVA NELLY;JOSHI OMKAR;WU PAUL;WANG DEQIAN;DESPONDS ARNAUD
分类号 A61K38/37 主分类号 A61K38/37
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