| 发明名称 |
SELECTIVE CYP11B1 INHIBITORS FOR THE TREATMENT OF CORTISOL DEPENDENT DISEASES |
| 摘要 |
The present invention relates to compounds which selectively inhibit CYP11B1. Preferably, the compounds of the present invention do not substantially inhibit CYP11B2. Moreover, the compounds of the present invention do not substantially inhibit CYP17 and/or CYP19, either. Amongst other applications of the compounds of the present invention, they can be used for the treatment of Cushing's syndrome or metabolic disease. |
| 申请公布号 |
EP2630136(A1) |
申请公布日期 |
2013.08.28 |
| 申请号 |
EP20110784441 |
申请日期 |
2011.10.21 |
| 申请人 |
UNIVERSITAET DES SAARLANDES |
发明人 |
HARTMANN, ROLF;HILLE, ULRIKE;ZIMMER, CHRISTINA;VOCK, CARSTEN A.;HU, QINGZHONG |
| 分类号 |
C07D401/06;A61K31/4164;A61P25/28;C07D409/14 |
主分类号 |
C07D401/06 |
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