Recombinant Production of Heparin Binding Proteins
摘要
A process for recovering and purifying refolded heparin binding proteins produced in heterologous host cells includes the step of incubation of the solubilized protein with a polyanionic species such as dextran sulfate.
申请公布号
US2013217867(A1)
申请公布日期
2013.08.22
申请号
US201313850641
申请日期
2013.03.26
申请人
GENENTECH, INC.;GENENTECH, INC.
发明人
BUTLER MICHELLE D.;CLELAND JEFFREY L.;KAHN DAVID W.;PIZARRO SHELLY;SCHMELZER CHARLES H.;WINKLER MARJORIE E.