PHARMACEUTICAL COMPOSITION AND METHOD OF TREATING DRY EYE DISORDER

摘要

PROBLEM TO BE SOLVED: To provide inhibitors of Janus kinase-3 ("Jak3") useful for treating dry eye disorders and other disorders requiring the wetting of the eye.SOLUTION: Jak3 inhibitors useful for treating eye disorders include the compound 3-{(3R,4R)-4-methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl}-3-oxo-propionitrile.