发明名称 |
P2X4 RECEPTOR ANTAGONIST |
摘要 |
<p>A compound having the following formula (II) or a pharmacologically acceptable salt thereof is used as a P2X 4 receptor antagonist:
wherein each of R 11 and R 12 is hydrogen, C 1-8 alkyl or the like;
R 13 is hydrogen, C 1-8 alkyl or the like;
R 14 is C 1-8 alkoxy, hydroxyl, cyano, a heterocyclic group optionally having a substituent or the like; and
the condensed ring consisting of W 1 and the neighboring benzene ring is naphthalene ring or the like.</p> |
申请公布号 |
EP2617717(A1) |
申请公布日期 |
2013.07.24 |
申请号 |
EP20110814504 |
申请日期 |
2011.07.27 |
申请人 |
NIPPON CHEMIPHAR CO., LTD. |
发明人 |
USHIODA, MASATOSHI;SAKUMA, SHOGO;IMAI, TOSHIYASU;INOUE, KAZUHIDE |
分类号 |
C07D239/70;A61K31/517;A61K31/519;A61P25/04;C07D401/04;C07D403/04;C07D403/10;C07D413/04;C07D471/04 |
主分类号 |
C07D239/70 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|