发明名称 |
CELL MODEL BASED ON STAT3 AND NF-kB DUAL-SIGNALLING PATHWAY AS TARGET FOR SCREENING ANTI-TUMOUR DRUG AND CONSTRUCTION AND USE THEREOF |
摘要 |
<p>Provided is a cell model based on a STAT3 and NF-kappaB dual-signaling pathway as the target for high-throughput anti-tumour drugs screening. The model is constructed by employing a STAT3-specific binding sequence and an NF-kappaB-specific binding sequence to establish a reporter-system vector being then combined with an active cell which has constitutive STAT3 and NF-kappaB simultaneously.</p> |
申请公布号 |
WO2013087033(A1) |
申请公布日期 |
2013.06.20 |
申请号 |
WO2012CN86710 |
申请日期 |
2012.12.15 |
申请人 |
LANZHOU UNIVERSITY |
发明人 |
YANG, JINBO;WANG, QIN;DU, YUPING;CHEN, XING |
分类号 |
C12N5/10;C12N15/11;C12N15/63 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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