发明名称 HER2/NEU-SPECIFIC ANTIBODIES AND METHODS OF USING SAME
摘要 5 This invention relates to antibodies that specifically bind HER2ineu, andparticularly chimeric 405 antibodies to HERThieu, which have reduced glycosylation as compared to known 4D5 antibodies. The invention also relates to methods of using the 4D5 antibodies and compositions comprising them in the diagnosis, prognosis and therapy of diseases such as cancer, autoimmune diseases, 10 inflammatory disorders, and infectious disease. Figure No. 13
申请公布号 SG189730(A1) 申请公布日期 2013.05.31
申请号 SG20130024161 申请日期 2009.03.25
申请人 MACROGENICS, INC. 发明人 JOHNSON, LESLIE, S.;HUANG, LING;TUAILLON, NADINE;BONVINI, EZIO
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