发明名称 |
Synergistic Anti-Cancer Activity of SR16388 with Anti-Mitotic Drugs |
摘要 |
The invention provides methods and compositions for inhibiting tumor growth in a mammal. The methods comprise administering to the mammal a synergistic combination of (E)-3-hydroxy-21-[2'-(N,N-dimethylamino)ethoxy]-19-norpregna-1,3,5(10),17(20)-tetraene and a microtubulin inhibitor like paclitaxel or vincristine. The combination of the compounds more than additively inhibits growth of tumor cells.
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申请公布号 |
US2013123222(A1) |
申请公布日期 |
2013.05.16 |
申请号 |
US201213674071 |
申请日期 |
2012.11.11 |
申请人 |
SRI INTERNATIONAL, INC.;SRI INTERNATIONAL, INC. |
发明人 |
ZHOU WEI;SAMBUCETTI LIDIA |
分类号 |
A61K31/57;A61K31/337;A61K31/475 |
主分类号 |
A61K31/57 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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