Disclosed herein are markers associated with sensitivity to treatment with proteasome inhibitors. Sensitivity is observed when RAS gene is wild type in tumor cells. Compositions and methods are provided to assess markers of marker genes to predict outcome with proteasome inhibition treatment
申请公布号
WO2013071163(A2)
申请公布日期
2013.05.16
申请号
WO2012US64520
申请日期
2012.11.09
申请人
MILLENNIUM PHARAMACEUTICALS, INC.
发明人
BERGER, ALLISON;BERNARD, HUGHES;CHATTOPADHYAY, NIBEDITA;KOENIG, ERIK, M.;MULLIGAN, GEORGE, J.;SCHU, MATTHEW, C.