摘要 |
A method of making a stent, including preparing a solution containing a composition, the composition comprising a biodegradable polymer and a vascular intimal hyperplasia inhibitor of a kind, including argatroban, which does not inhibit proliferation of endothelial cells, the weight compositional ratio of the polymer to the vascular intimal hyperplasia inhibitor being within the range of 8:2 to 3:7, the composition dissolved in a solvent selected from the group consisting of a mixture of a lower alkyl ketone and methanol, a mixture of a lower alkyl ester and methanol or a mixture of a lower halogenated hydrocarbon and methanol; coating at least an outer surface of a stent body of a cylindrical configuration having outer and inner surfaces with a diamond-like thin film coated on the surfaces; and after the coating, removing the solvent to complete a first coated layer.
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申请人 |
JAPAN STENT TECHNOLOGY CO., LTD.;TOKAI UNIVERSITY EDUCATIONAL SYSTEM;TOYO ADVANCED TECHNOLOGIES CO., LTD.;HIROO IWATA;TOYO ADVANCED TECHNOLOGIES CO., LTD.;TOKAI UNIVERSITY EDUCATIONAL SYSTEM;JANPAN STENT TECHNOLOGY CO., LTD. |
发明人 |
OMURA IKUO;JIN ZHEN YU;YAMASHITA SHUZO;IWATA HIROO;MOCHIZUKI AKIRA |