Human anti-B7RP1 neutralizing antibodies

摘要

HUMAN ANTI-B7RP1 NEUTRALIZING ANTIBODIES This invention provides antibodies that interact with or bind to human B7 related protein-I (B7RP1) and antibodies that bind to and neutralize the function of B7RP1 thereby. The invention 5 also provides pharmaceutical compositions of said antibodies and methods for neutralizing B7RP 1 function, and particularly for treating immune disorders (e.g., inappropriate immune response) by administering a pharmaceutically effective amount of anti-B7RP 1 antibodies. Methods of detecting the amount of B7RP 1 in a sample using anti-B7RP 1 antibodies are also provided.