| 发明名称 |
Positive allosteric modulators of the alpha 7 nicotinic acetylcholine receptor and uses thereof. |
| 摘要 |
<p>The present invention relates to compounds of formula (I) with the substituents as described within the specification. The compounds are useful in the positive modulation of the alpha 7 nicotinic acetylcholine receptor (α7nAChR). The invention also relates to the use of these compounds in the treatment or prevention of a broad range of diseases in which the positive modulation ofα7nAChR is advantageous, including neurodegenerative and neuropsychiatric diseases and also inflammatory diseases.</p> |
| 申请公布号 |
AU2012212393(A1) |
申请公布日期 |
2013.03.14 |
| 申请号 |
AU20120212393 |
申请日期 |
2012.02.02 |
| 申请人 |
BIONOMICS LIMITED |
发明人 |
HARVEY, ANDREW;FLUCK, AUDREY;GIETHLEN, BRUNO;PAUL, DHARAM;SCHAEFFER, LAURENT |
| 分类号 |
C07C233/57;A61K31/167;A61K31/36;A61K31/415;A61K31/426;A61K31/44;A61K31/4409;A61K31/63;A61P25/00;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P29/00;C07C233/60;C07D213/81;C07D213/82;C07D231/40;C07D277/46;C07D317/58 |
主分类号 |
C07C233/57 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
