发明名称 |
PHOTOLUMINESCENT NANOSTRUCTURE-BASED SENSORS |
摘要 |
A composition for sensing an analyte can include a photoluminescent nanostructure complexed to a sensing polymer, where the sensing polymer includes an organic polymer non-covalently bound to the photoluminescent nanostructure and an analyte-binding protein covalently bound to the organic polymer, and where the analyte- binding protein is capable of selectively binding the analyte, and the analyte-binding protein undergoes a substantial conformational change when binding the analyte. Separately, a composition for sensing an analyte, can include a complex, where the complex includes a photoluminescent nanostructure in an aqueous surfactant dispersion and a boronic acid capable of selectively reacting with an analyte. The compositions can be used in devices and methods for sensing an analyte. |
申请公布号 |
CA2843950(A1) |
申请公布日期 |
2013.02.07 |
申请号 |
CA20122843950 |
申请日期 |
2012.07.30 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
STRANO, MICHAEL S.;BARONE, PAUL W.;AHN, JIN-HO;YUM, KYUNGSUK;MCNICHOLAS, THOMAS P. |
分类号 |
G01N33/66;A61B5/145 |
主分类号 |
G01N33/66 |
代理机构 |
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