| 发明名称 |
Morpholino substituted urea derivatives as mtor inhibitors |
| 摘要 |
<p>The invention relates to compounds of formula (I) wherein X1, X2, R1 to R4, m, n have the meaning as cited in the description and the claims. Said compounds are useful as inhibitors of mTOR for the treatment or prophylaxis of mTOR related diseases and disorders. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the use as medicaments.</p> |
| 申请公布号 |
EP2542536(A1) |
申请公布日期 |
2013.01.09 |
| 申请号 |
EP20110706815 |
申请日期 |
2011.03.04 |
| 申请人 |
CELLZOME LIMITED |
发明人 |
LYNCH, ROSEMARY;CANSFIELD, ANDREW, DAVID;NIBLOCK, HELEN, SARAH;HARDY, DANIEL, PAUL;TAYLOR, JESSICA |
| 分类号 |
C07D239/42;A61K31/5377;A61P37/00;C07D401/04;C07D413/04;C07D413/14;C07D498/08 |
主分类号 |
C07D239/42 |
| 代理机构 |
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代理人 |
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| 主权项 |
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